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Symbol
Name
ID

Npm1
nucleophosmin 1
MGI:106184

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Acute myeloid leukemia
Disease(s) Associated with NPM1	Acute myeloid leukemia
acute myeloid leukemia

Mouse Phenotypes		abnormal granulocyte differentiation	enlarged spleen	increased spleen weight	abnormal thrombopoiesis	myeloid hyperplasia	increased granulocyte number	decreased B cell number	increased monocyte cell number	increased leukocyte cell number	abnormal spleen B cell follicle morphology
Availability	Mouse Genotype	abnormal granulocyte differentiation	enlarged spleen	increased spleen weight	abnormal thrombopoiesis	myeloid hyperplasia	increased granulocyte number	decreased B cell number	increased monocyte cell number	increased leukocyte cell number	abnormal spleen B cell follicle morphology
	Npm1^tm1Hft/Npm1⁺
	Npm1^tm1Ppp/Npm1⁺
	Npm1^tm1Gsva/Npm1⁺ Tg(Mx1-cre)1Cgn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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